![]() ![]() The results of allergy tests were summarized in Table 1. Basophil activation test was performed with various concentrations of synthetic taurine (0.2-20 mg/mL), but the results were negative. Skin prick test with synthetic taurine and natural taurine (20 mg/mL, the same concentration with Drink A) showed negative responses. However, the patient had no symptom or sign with 1,500 mg natural taurine and 45 mg nicotiniamide as the cumulative dose. We performed oral challenge test with another taurine-containing energy drink ("Drink D" in Table 1) which the patient never had drunken, and the result was positive. ![]() On the test with synthetic taurine, she had itching on her face and palm with erythema at 30 min after ingestion of 1,000 mg synthetic taurine. The laboratory in the manufacturing company of Drink B offered us synthetic taurine, natural taurine and nicotiniamide in powder form. Oral challenge test with synthetic taurine, natural taurine and nicotiniamide were performed on different days. We investigated the common ingredients in Drink A (synthetic taurine 20 mg/mL) and B (synthetic taurine 20 mg/mL), and found that both drinks contain synthetic taurine and nicotiniamide (the maximum dosages are 2,000 mg and 50 mg, respectively). We concluded that the oral challenge test was positive. ![]() At 90 min, she had facial itching and angioedema on her lips. At 50 min after ingestion of 50 mL, the patient complained of itching on her both palms with erythema. The first, oral challenge test with Drink B was performed to ascertain that the patient had allergic reaction actually. There was no family member of food or respiratory allergy and she was working at a bank. History of food allergy and any other diseases were denied by the patient. Complete blood count, liver function test, renal function test and serum electrolytes were within normal limits and serum total IgE level was elevated to 685 IU/mL. When visiting our clinic, the patient had no remained symptom and showed no abnormality on the physical examination. She had experienced similar symptoms after drinking another beverage ("Drink B" in below) which was commonly used for hangover 2 years before the event. The patient experienced generalized itching, urticaria, dyspnea and dizziness 10 min after ingestion of a bottle (100 mL) of energy drink ("Drink A" in below) and then she was treated in the emergency department of a nearby hospital. A 33-year-old female patient visited allergy clinic in Seoul National University Bundang Hospital because of an event happened on her summer vacation. ![]()
0 Comments
Leave a Reply. |